According to embodiments, sensors and systems for medical spectroscopy may include adaptive optical components, such as digital light processing components. Adaptive light emitting elements may allow such sensors to alter the intensity profile of emitted light photons to change the distribution of photons through the tissue or to scan areas of tissue to determine if certain areas may be associated with improved measurements. In addition, sensors with adaptive light detecting elements as provided may adapt to selectively detect light of certain wavelengths or from certain regions of the tissue.