A self-destroying disposable syringe (100) includes a barrel (20) which includes a hub (23) disposed on the front end of the barrel (20), a flange (24) is disposed on the inner wall of the hub (23) a needle base(10) which connects to the hub (23) of the barrel (20), and includes a connecting portion (13), a containing portion (14) disposed on the outer side of the connecting portion (13), and a self-destroying ring (15) disposed on the back end of the needle base (10) and connected to the connecting portion (13) through one or more ribs (16) when the needle base (10) has connected to the barrel (20), the connecting portion (13) and the self-destroying ring (15) are located in the inside of the hub (23) of the barrel (20), and the self-destroying ring (15) matches the flange (24) each other a plunger (30) which is movably inserted into the barrel (20) and includes a bar body (31), a pushing stem (32) connected to the back end (31b) of the bar body (31), a pushing dish (33) connected to the front end (31a) of the bar body (31), a cone (34) with one end fixed to the pushing disc (33), and a puncturing portion (35) fixed to the other end of the cone (34) and a piston (40) which is connected to the cone (34) of the plunger (30), a cavity (45) is provided within the piston (40) a sealed front wall (43) is provided on the front end (41) of the piston (40), an opening (46) communicated with the cavity (45) is provided on the back end (42) of the piston (40).