Methods for the induction of ebola virus-specific immune responses comprising administering a replication-defective chimpanzee adenovirus vector expressing the ebola virus glycoprotein
Nancy J. Sullivan,Gary J. Nabel,Clement Asiedu,Cheng Cheng,Alfredo Nicosia,Riccardo Cortese,Virginia Ammendola,Stefano Colloca
申请号:
US13641655
公开号:
US09526777B2
申请日:
2011.04.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebola virus (EBOV) or Marburg virus (MARV).