Sever Nancy,WESTEDT ULRICH,LANDER UTE,SCHNEIDER KATRIN,STEITZ BENEDIKT,MUELLER THOMAS,REUL REGINA,Obermiller Constanze,JAYASANKAR ADIVARAHA,SIMON MICHAEL,GAO YI,HACH HARALD,KYEREMATENG SAMUEL,ASMUS KA
申请号:
IN201817002543
公开号:
IN201817002543A
申请日:
2018.01.22
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1 as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2 as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant all of which are formulated in amorphous solid dispersion.