International Business Machines Corporation;Agency for Science, Technology and Research
发明人:
James L. Hedrick,Nathaniel H. Park,Yi Yan Yang,Zhi Xiang Voo
申请号：
US16201155
公开号：
US20200164080A1
申请日:
2018.11.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The subject disclosure is directed to techniques for enhancing the selectivity and efficacy of therapeutic polymers against a broad spectrum of pathogens and cancer cell lines. According to an embodiment, a method is provided that comprises forming a therapeutic polymer based on polymerization of a plurality of therapeutic monomers, wherein the therapeutic polymer provides a therapeutic functionality. The method further comprises attaching biotin to the therapeutic polymer, resulting in a biotin-functionalized therapeutic polymer, wherein the biotin-functionalized therapeutic polymer provides greater therapeutic efficacy relative to the therapeutic polymer.
