Ananda G. Lugade;Daniel R. Draney;Narasimhachari Narayanan;Joy Kovar;D. Michael Olive
发明人:
Daniel R. Draney,Ananda G. Lugade,Narasimhachari Narayanan,Joy Kovar,D. Michael Olive
申请号：
US13525136
公开号：
US08303936B2
申请日:
2012.06.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.
