Bright offer formula (I) compound of this Hair or its can Drug Yong Which; System makes the method for the compound and its controls Treatment purposes. Mono- step of this Hair Ming Jin provides Drug Li Learn activity Elixirs Group conjunction and the Drug Wu Group comprising the compound closes object.本發明提供式(I)化合物或其可藥用鹽;製造所述化合物的方法及其治療用途。本發明進一步提供藥理學活性劑的組合以及包含所述化合物的藥物組合物。