內蓋夫國家生物技術研究所;THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD
发明人:
SHOSHAN-BARMATZ, Varda,LEV GRUZMAN, Arie,A．列弗古斯曼
申请号：
HK18116285
公开号：
HK1257495A1
申请日:
2018.12.19
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
Provided herein piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction. Also provided methods of treatment of diseases associated with said processes, e.g. Alzheimer's disease.
