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COMPOSITION POUR STABILISER UNE PROTÉINE DE FUSION DANS LAQUELLE UNE PROTÉINE ET UN DOMAINE FC SONT FUSIONNÉS
专利权人:
ALTEOGEN; INC
发明人:
PARK, SOON JAE,KIM, SEONG-KYU
申请号:
EP13857947
公开号:
EP2926834A4
申请日:
2013.10.23
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to a composition for stabilizing a fusion protein of a physiologically active protein and an Fc domain, and more particularly to a method of stabilizing a fusion protein of a protein and an Fc domain using a composition containing an ammonium salt or a combination of an ammonium salt and succinate. The composition containing an ammonium salt or a combination of an ammonium salt and succinate according to the present invention can effectively inhibit the aggregation of the protein-Fc domain fusion protein, and thus enables the fusion protein to be stored for a long period of time. Accordingly, the composition can be widely used in the medical field that uses the protein-Fc domain fusion protein.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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