PROBLEM TO BE SOLVED: To provide pharmaceutical compositions comprising a compound useful for treatment of diseases associated with β2 integrin.SOLUTION: A pharmaceutical composition comprises a compound represented by the formula in the figure. [B is methylene and R1 is phenyl or the like; X is O or S; and each R is chlorine or the like.]SELECTED DRAWING: None【課題】β2インテグリンに関連する疾患の治療に有用な化合物を含む医薬組成物の提供。【解決手段】下記式で表される化合物を含有する医薬組成物。[Bはメチレン且つR1はフェニル等;XはO又はS;各Rは塩素等]【選択図】なし