Thomas W. Dubensky, Jr.;Dirk G. Brockstedt;Meredith Leong;Keith S. Bahjat
发明人:
Thomas W. Dubensky, Jr.,Dirk G. Brockstedt,Meredith Leong,Keith S. Bahjat
申请号:
US12374288
公开号:
US08926993B2
申请日:
2007.07.17
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.