The invention provides compositions and methods for administering compounds for transmucosal absorption. The compositions and methods have a number of surprising pharmacokinetic benefits over oral administration of a compound.本發明提供用於投與化合物供穿黏膜吸收之組合物及方法。該等組合物及方法具有許多優於經口投與化合物之驚人藥物動力學益處。