Scott W. Cousins,David M. Gooden,Priyatham S. Mettu
申请号:
US15016623
公开号:
US09879005B2
申请日:
2016.02.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure provides compositions and methods for treating ocular disorders in mammals especially in and not limited to humans and mice. The present disclosure further provides methods of treating cancer and appetite suppression using the compositions which are novel small molecule inhibitors of CaMKK2. In addition, these derived compositions can regulate non-ocular disorders, such as cancer and appetite suppression by modulating and inhibiting CaMKK2 and the regulation of the macrophage mediated diseases.