The present invention relates an injectable parenteral pharmaceutical composition of trabectedin and preparation method thereof. Specifically, the pharmaceutical composition comprising trabectedin and the first excipient, the first excipient selects from one or more monosaccharide or polyhydric alcohol. The preparation of the invention has stable quality and is suitable for industrial production.本發明涉及一種曲貝替定的可注射胃腸外用藥物組成物及其製備方法。具體而言，該組成物包含曲貝替定和第一賦形劑，該第一賦形劑選自單糖或多元醇的一種或幾種。本發明的製劑品質穩定，適用於工業化大生產。
