Scott Gallichan,Belma Ljutic,Martina Ochs-Onolemhemhen,Marie-Danielle Salha,Robert Hopfer,Lee-Jah Chang
申请号：
US15124417
公开号：
US20170157233A1
申请日:
2015.03.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
This disclosure relates to immunogenic compositions comprising an isolated immunogenic S. pneumoniae PcpA polypeptide, at least one additional antigen (such as for example, an isolated immunogenic S. pneumoniae polypeptide selected from the group consisting of the polyhistidine triad family of proteins (e.g., PhtD), and at least one isolated detoxified pneumolysin (e.g., PlyD1) and methods of using these compositions for preventing and treating diseases caused by S. pneumoniae.
