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Glycopeptides DERIVED FROM pancreatic STRUCTURES, ANTIBODIES AND APPLICATIONS THEREOF IN DIAGNOSIS AND therapeutics
专利权人:
Université d'Aix-Marseille;I.N.S.E.R.M. Institut National de la Santé et de la Recherche Médicale
发明人:
MAS, Eric,SADOULET, Marie-Odile,PANICOT-DUBOIS, Laurence,BERNARD, Jean-Paul,LOMBARDO, Dominique
申请号:
DK05746926
公开号:
DK1730270T3
申请日:
2005.03.30
申请国别(地区):
DK
年份:
2016
代理人:
摘要:
Glycopeptide comprising 1 to 40 repeated C-terminal polypeptides, with 11 amino acids, of BSDL or FAPP, whereby said polypeptides are glycosylated and bear glycosylated epitopes giving rise to a specific immunological reaction with induced antibodies in a patient suffering from type 1 diabetes and/or purified from biological fluids of human or animal origin or recombinant and produced by expression in a standard host cell comprising an enzymatic material necessary for priming a glycosylation, said host cell being genetically modified such as to comprise a gene coding for said polypeptides and a gene coding for one or more enzymes selected from among glycosyltransferases, anti-glycopeptide antibodies and the applications thereof in therapeutics and diagnostics.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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