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Methods and Kits for Predicting Infusion Reaction Risk and Antibody-Mediated Loss of Response by Monitoring Serum Uric Acid During Pegylated Uricase Therapy
专利权人:
David Erick Wright;Theresa Rosario-Jansen
发明人:
Theresa Rosario-Jansen,David Erick Wright
申请号:
US13379704
公开号:
US20120301454A1
申请日:
2010.06.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response during intravenous PEGylated uricase therapy in gout patients is provided. Routine SUA monitoring can be used to identify patients receiving PEGylated uricase who may no longer benefit from treatment and who are at greater risk for infusion reactions.
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