ANTI-CANCER EFFECTS OF PROTEASOME INHIBITORS IN COMBINATION WITH GLUCOCORTICOIDS, ARSENIC CONTAINING COMPOUNDS, AND ASCORBIC ACID

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专利权人:

发明人:

申请号：

EP15807258.7

公开号：

EP3154596A4

申请日:

2015.06.10

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention provides methods of treatment for hematological malignancies involving synergistic combination of a proteasome inhibitor, a glucocorticoid, an arsenic-containing compound, and ascorbic acid or a derivative thereof provide an unexpected efficacy in the treatment for hematological disorders. The hematological disorders treated by the current invention include multiple myeloma, and may also include hematological disorders that are refractory to prior cancer treatments, or relapsed hematologic disorders.

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