Provided is a composition for improving and/or treating central nervous system degenerative disease associated with learning and memory impairment. A composition for improving and/or treating central nervous system degenerative disease, containing as an active ingredient at least one compound selected from: compound (S4) (sinensetin) in which R1, R2, R3, and R4 in general formula (I) are methoxy groups and R5 is H； compound (S3) (6-demethoxytangeretin) in which R2, R4, and R5 are methoxy groups and R1 and R3 are H； and compound (S2) (6-demethoxynobiletin) in which R1, R2, R4, and R5 are methoxy groups and R3 is H.
