Cameron Peter Sean,Haurwitz Rachel E.,May Andrew P.,Nye Christopher H.,van Overbeek Megan
申请号：
US201514836753
公开号：
US9970030(B2)
申请日:
2015.08.26
申请国别(地区):
美国
年份:
2018
代理人:
Fabian Gary R.`McClung Barbara G.
摘要：
Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid.
