Carboxamide compounds and their use as calpain inhibitors

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专利权人:

AbbVie Inc.;AbbVie Deutschland GmbH & Co. KG

发明人:

Kling, Andreas,Jantos, Katja,Mack, Helmut,Moller, Achim,Hornberger, Wilfried,Backfisch, Gisela,Lao, Yanbin,Nijsen, Marjoleen

申请号：

AU2010334915

公开号：

AU2010334915B2

申请日:

2010.12.21

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R

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