Barnscheid, Lutz,Schwier, Sebastian,Bartholomaus, Johannes
申请号:
AU2011297954
公开号:
AU2011297954B2
申请日:
2011.09.01
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The invention relates to a pharmaceutical dosage form exhibiting a breaking strength of at least 500 N, said dosage form containing - a pharmacologically active ingredient (A) - an anionic polysaccharide (B) obtainable by introducing anionic functional groups, in protonated form or a physiologically acceptable salt thereof, into a polysaccharide and - a polyalkylene oxide (C) wherein the pharmacologically active ingredient (A) is present in a controlled-release matrix comprising the anionic polysaccharide (B) and the polyalkylene oxide (C).