Disclosed are compositions and methods for the use of adiponectin peptidomimetics in therapeutic applications. The compositions can include a peptide, for example, D-Asn-Ile-Pro-Nva-Leu-Tyr-D-Ser-Phe-Ala-D-Ser-NH2, a solubilizer, a surfactant(s), a buffer, optionally boric acid and optionally mannitol. The osmolality of the composition can be between 260 to 330 mOsm/kg and the pH can be between 4.5 to 5.5. Methods of using the compositions in treating certain eye disease(s) are also disclosed.本發明揭示用於治療性應用中之脂聯素擬肽之組合物及方法。該等組合物可包括肽，例如D-Asn-Ile-Pro-Nva-Leu-Tyr-D-Ser-Phe-Ala-D-Ser-NH2、增溶劑、一或多種界面活性劑、緩衝劑、視情況選用之硼酸及視情況選用之甘露醇。該組合物之重量莫耳滲透濃度可在260至330 mOsm/kg之間且pH值可在4.5至5.5之間。本發明亦揭示使用該等組合物治療某種或某些眼部疾病之方法。
