A specimen retrieval device includes a tubular body (12) defining a longitudinal bore, an inner shaft slidably disposed within the longitudinal bore of the tubular body (12), and a specimen bag (70) affixed to a support mechanism (28) at the distal portion of the inner shaft. The specimen bag (70) has an opening (75) capable of being closed by a linkage assembly after placement of tissue therein, but prior to removal of the device from the body.
