Compounds derived from 5.7 - dihydro - 5h pyrrolo [2,3-d] pyrimidine 6 - ona,Modulators of the production of cyclic guanosine monophosphate (CMPC), its Pharmaceutical composition, useful in the treatment of cardiovascular diseases, endothelial dysfunction and diastolicHypertension, thrombosis, atherosclerosis, angina pectoris, among others.
RAGHAVAN SUBHAREKHA,STELMACH JOHN E.,SMITH CAMERON J.,LI HONG,WADDEL SHERMAN T.,CHEN YI-HENG,MIAO SHOUWU,ORNOSKI OLGA A.,GARFUNKLE JOIE,LIAO XIBIN,CHANG JIANG,HAN XIAOQING,GUO JIAN,GROEPER JONATHAN A.
申请号：
CL2012003317
公开号：
CL2012003317A1
申请日:
2012.11.27
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
Heteroaryl compounds derived from pyrrolo [2,3-d] pyrimidine 6 - ona,Modulators of soluble guanylate cyclase, Pharmaceutical compositions, and Method for Treatment of one or more selected Conditions between endothelial dysfunction, cardiovascular diseases,Among others.Compuestos derivados de heteroaril-pirrolo[2,3-d]pirimidin-6-ona, moduladores de la guanilato ciclasa soluble； composiciones farmacéuticas； método para el tratamiento de una o más condiciones seleccionadas entre enfermedades cardiovasculares, disfunción endotelial, entre otras.
