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Pharmaceutical composition for cancer treatment and pharmaceutical preparation for cancer treatment comprising the composition as an active ingredient
专利权人:
株式会社Quarrymen&Co.;株式会社Quarrymen&Co.
发明人:
上田 実
申请号:
JP2015559139
公开号:
JP6166388B2
申请日:
2015.01.23
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
The purpose of the present invention is to provide a novel anticancer therapeutic having a high effect against solid cancers, lacking the side effects of chemotherapeutics, and being unlikely to cause resistance. Provided is a pharmaceutical composition for cancer treatment prepared by a method having: a stem cell production step for making immortalized stem cells by introducing four types of genes into deciduous tooth dental pulp stem cells obtained from the dental pulp of mammals; and a condition medium preparation step for culturing the immortalized stem cells for a predetermined length of time in serum-free medium at 23-27°C under conditions of low oxygen concentration at an oxygen concentration of from 0.5% to less than 20%, the pharmaceutical composition containing 1.5 times or more of insulin-like growth factor (IGF-1) and vascular endothelial growth factor (VEGF) than is contained in condition medium prepared when culturing at an oxygen concentration of 20% and otherwise identical conditions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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