Gregory D. Lundquist, Jr.;Michael E. Danielson;Shri Niwas;Tushar A. Kshirsagar;Bryon A. Merrill;Philip D. Heppner
发明人:
Tushar A. Kshirsagar,Bryon A. Merrill,Shri Niwas,Gregory D. Lundquist, Jr.,Philip D. Heppner,Michael E. Danielson
申请号:
US11885006
公开号:
US08158794B2
申请日:
2006.02.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Certain imidazoquinolines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, and an aryl or heteroaryl substituent at the 7-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-α biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.