An instrument for prevention and treatment of periodontal disease. The instrument comprises a supporting frame (1), a power supply controller (2), a medication generator (3), a liquid medicine generation device (41, 42, 43), a booster pump (5), and a working head (71, 72, 73). The liquid medicine generation device (41, 42, 43) comprises a liquid medicine solvent tank (41), a submersible pump (42), and a liquid medicine generation barrel (43). The submersible pump (42) is connected between the liquid medicine solvent tank (41) and the liquid medicine generation barrel (43) and has the function of pumping a liquid medicine solvent into the liquid medicine generation barrel (43) from the liquid medicine solvent tank (41). A liquid medicine generation barrel aerator (31) of the medication generator (3) is connected to the liquid medicine generation barrel (43) by means of a tube, so that a medication can be fully dissolved in the liquid medicine solvent. The booster pump (5) is connected between the working head (71, 72, 73) and the liquid medicine generation barrel (43) for pumping liquid medicine into the working head (71, 72, 73) from the liquid medicine generation barrel (43). The instrument is used for preventing and treating periodontal disease, and ozone is used in the instrument for prevention and treatment of periodontal disease. Moreover, the instrument for prevention and treatment of periodontal disease further has an ultrasonic tooth cleaning function, and the ultrasonic tooth cleaning function and an ozone treatment function are combined for prevention and treatment thus, periodontal disease can be prevented and treated more effectively.La présente invention concerne un instrument pour la prévention et le traitement dune maladie parodontale. Linstrument comprend un cadre de support (1), un dispositif de commande dalimentation électrique (2), un générateur de médicament (3), un dispositif de génération de médicament liquide (41, 42, 43), une pompe de surpres