YOUN, HWA YOUNGKR,윤화영,LEE, HEE WOOKR,이희우,HAN, SEI MYOUNGKR,한세명,JANG, GOOKR
申请号：
KR1020150087242
公开号：
KR1020160034176A
申请日:
2015.06.19
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
Disclosed in the present invention are: a mesenchymal stem cell for overexpressing Oct4 and Sox2 and uses as a cell therapy product thereof. According to the present invention, the mesenchymal stem cell for overexpressing Oct4 and Sox2 has the significantly improved proliferation ability and the ability to differentiate into fat cells, osteoblasts, and liver cells. Particularly, the cell is expected to have effects in improving liver functions damaged by liver diseases, and in promoting the regeneration, by being used for treating chronic liver diseases such as liver cirrhosis.COPYRIGHT KIPO 2016본원은 Oct4와 Sox2를 과발현하는 중간엽줄기세포 및 이의 세포치료제로서의 용도를 개시한다. 본원에 따른 Oct4와 Sox2를 과발현하는 중간엽줄기세포는 증식능과 지방세포, 골세포 및 간세포로의 분화능이 월등히 향상되어, 특히 간경변증과 같은 만성간질환의 치료에 사용되어, 간질환에 의해 손상된 간 기능을 개선하고 재생 촉진효과를 기대할 수 있다.
