The present invention includes cancer angiogenesis, rheumatoid arthritis, intimal thickening, vascular atherosclerosis, hemorrhagic stroke, acute myocardial infarction, chronic heart failure, aneurysm, cancer metastasis, adult respiratory distress syndrome, asthma, It is an object to provide a novel compound or a pharmaceutically acceptable salt thereof useful for the prevention or treatment of diseases such as idiopathic pulmonary fibrosis, chronic sinusitis, bronchitis, or chronic obstructive pulmonary disease. The present invention provides a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.本発明は、癌性血管新生、慢性関節リウマチ、血管内膜肥厚、血管粥状硬化症、出血性型の脳卒中、急性心筋梗塞、慢性心不全、動脈瘤、癌転移、成人呼吸窮迫症候群、喘息、特発性肺線維症、慢性副鼻腔炎、気管支炎、又は慢性閉塞性肺疾患等の疾患の予防又は治療に有用な新規な化合物又はその医薬上許容される塩を提供することを目的とする。本発明は、式（Ｉ）で表される化合物又はその医薬上許容される塩を提供する。
