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MEDICINAL FORM FOR TRANSMISSIONAL ORAL ADMINISTRATION OF ANALGETIC AND / OR ANTI-SPASMATIC MOLECULES
专利权人:
МОРИ Марк (FR);ПЕРОВИЧ Филипп (FR)
发明人:
ПЕРОВИЧ Филипп (FR),МОРИ Марк (FR)
申请号:
RU2011134033/15
公开号:
RU2011134033A
申请日:
2010.01.12
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. Dosage form for transmucosal oral administration of at least one active substance intended for the treatment of a spastic attack, including: - at least one active substance present in the form of a base and / or in the form of a salt, selected from among antispasmodics peripheral action or nefopam, - an aqueous-alcoholic solution with a strength of at least 35 ° alcohol, and, if necessary, another active substance present in the form of a base and / or in the form of a salt, selected from as centrally acting analgesics, in which the active ingredient or active ingredients is present (dissolved) in a state of stable and complete dissolution in a hydroalcoholic rastvore.2. Dosage form according to claim 1, characterized in that the antispasmodic agents of peripheral action are selected from among thiemone or phloroglucin. Dosage form according to claim 1 or 2, characterized in that the central-acting analgesics are selected from paracetamol or nefopam. The dosage form according to claim 1 or 2, characterized in that the strength of the water-alcohol solution is from 35 to 70 ° alcohol. Dosage form according to claim 1 or 2, characterized in that the alcohol of the aqueous-alcoholic solution is ethanol. Dosage form according to claim 1 or 2, characterized in that it also includes a substance that corrects pH. The dosage form according to claim 6, characterized in that the pH-adjusting substance is selected from among sodium carbonates and bicarbonates, primary and secondary acid phosphates of sodium, triethanolamine, sodium hydroxide and potassium hydroxide and / or from acids: hydrochloric, sulfuric, yang1. Лекарственная форма для чресслизистого перорального введения, по меньшей мере, одного действующего вещества, предназначенного для лечения спастического приступа, включающая:- по меньшей мере, одно действующее вещество, присутствующее в форме основания и/или в форме соли, выбранное из числа антиспазматических средств периферического действия или нефопама,- водно-
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