PROBLEM TO BE SOLVED: To search out new medical uses of a compound represented by general formula (1) or a salt thereof.SOLUTION: The compound represented by general formula (1) or a salt thereof can exhibit an excellent prophylactic or ameliorative effect in models for corneal diseases and is useful for prophylactic or therapeutic agent for keratoconjunctival disorders such as dry eye, superficial punctate keratopathy, corneal epithelial loss, corneal erosion, corneal ulcer, conjunctival epithelial loss, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis, and conjunctivitis.COPYRIGHT: (C)2013,JPO&INPIT【課題】下記一般式(1)で表される化合物又はその塩の新たな医薬用途を探索する。【解決手段】下記一般式(1)で表される化合物又はその塩は、角膜障害モデルにおいて優れた予防又は改善効果を発揮し、ドライアイ、点状表層角膜症、角膜上皮欠損、角膜びらん、角膜潰瘍、結膜上皮欠損、乾性角結膜炎、上輪部角結膜炎、糸状角結膜炎、角膜炎、結膜炎などの角結膜障害の予防又は治療剤として有用である。【選択図】なし