Ronald T. Raines,Ian Windsor,Michael Palte,John Lukesh
申请号：
US14927390
公开号：
US09738664B2
申请日:
2015.10.29
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Protease inhibitors, particularly aspartyl protease inhibitors, and more particularly HIV protease inhibitors which are boronated to enhance activity or to enhance entry into cells. Compounds, prodrugs and salts thereof of this invention contain phenylboronate groups, in particular p -B(OH)2-phenyl groups, benzoxaborole groups or borono-pyridyl groups or analogous groups in which the boronate group is protected. Methods for treating AIDS and ARC as well as providing a method for treating or preventing HIV infection.
