593674 Disclosed is an immunogenic composition comprising (i) a meningococcal haemoglobin receptor (HmbR) antigen and (ii) one or more meningococcal antigen(s) selected from the group consisting of: factor H binding protein (fHBP)； 287； Neisserial adhesion A (NadA)； Neisserial surface protein A (NspA)； Neisseria hia homologue (NhhA)； Adhesion and penetration protein (App)； 85kDa outer membrane protein (Omp85)； and meningococcal lipo-oligosaccharide (LOS), and it's use in treating a Neisserial infection.
