STILES JONATHAN K,LILLARD JAMES W,ARMAH HENRY BENJAMIN A,WILSON NANA O,UDHAYAKUMAR VENKATACHALAM
申请号：
IN4716/CHENP/2013
公开号：
IN2013CN04716A
申请日:
2013.06.18
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
Biomarkers for predicting the severity of malaria and methods for their detection are disclosed. In one aspect the present application discloses CXCL4 CXCLIO VEGF PGDF IL lRa IL 8 sFas Fas L sTNF R2 and sTNF Rl as biomarkers for the severity of malaria. In another aspect the present application discloses a method for determining the severity of malaria and predicting mortality due to cerebral malaria. The method comprises the detection of the biomarkers CXCL4 and/or CXCLIO and at least one more biomarker and determining the severity of malaria and predicting mortality due to cerebral malaria based upon the ratio of expression of the biomarkers in the subject versus the expression of the biomarkers in a control.
