COMPOSES SUBSTITUES DE (4'-HYDROXYPHENYL)CYCLOALKANE ET LEURS UTILISATIONS EN TANT QU'AGONISTES SELECTIFS DE L'ISOFORME BETA DU RECEPTEUR D';STROGENES
CONCORDIA UNIVERSITY WISCONSIN;MARQUETTE UNIVERSITY
发明人:
DONALDSON, WILLIAM A.,SEM, DANIEL S.,NEUMANN, TERRENCE S.
申请号:
CA2931313
公开号:
CA2931313A1
申请日:
2014.11.21
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Disclosed are substituted (4'-hydroxylphenyl)cycloalkane compounds and there use as selective agonists of the estrogen receptor beta isoform (??ß). The disclosed compounds may be formulated as pharmaceutical compositions and administered to treat diseases associated with ERß activity, such as proliferative diseases and disorders and/or psychiatric diseases or disorders.