Adeno-associated virus purification methods

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专利权人:

Baxalta Incorporated;Baxalta GmbH

发明人:

FIEDLER, Christian,HASSLACHER, Meinhard,KOEHN, Jadranka

申请号：

AU2018395254

公开号：

AU2018395254A1

申请日:

2018.12.27

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

Provided herein are methods of producing an adeno-associated virus (AAV) product and methods of purifying adeno-associated virus. AAV is loaded onto an affinity resin, wash steps are undertaken, and AAV is eluted from the affinity resin. Various buffers are disclosed for use in the wash steps and elution.

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