CHILDREN'S HOSPITAL MEDICAL CENTER;CHILDRENS HOSPITAL MEDICAL CENTER
发明人:
WELLS, JAMES M.,HELMRATH, MICHAEL A.,MAHE, MAXIME MICKAEL,WATSON, CAREY L.,MUNERA, JORGE,WORKMAN, MICHAEL J.
申请号：
CA2963704
公开号：
CA2963704A1
申请日:
2015.10.16
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem cells (ESC's) and/or induced pluripotent stem cells (iPSCs), such that the HIO forms mature intestinal tissue. Also disclosed are methods for making a human intestinal tissue containing a functional enteric nervous system (ENS).
