BARSKE CARMEN,BARSKE Carmen,FRENTZEL STEFAN,FRENTZEL Stefan,MIR ANIS KHURSO,MIR Anis Khurso,SCHWAB MARTIN E.,SCHWAB Martin E.,VITALITI ALESSANDRA,VITALITI Alessandra
申请号：
SI200831001
公开号：
SI2207808T1
申请日:
2008.10.27
申请国别(地区):
SI
年份:
2013
代理人:
摘要：
The present invention provides a binding molecule which is capable of binding to the human NogoA polypeptide or human NiG with a dissociation constant<1000 nM, a polynucleotide encoding such binding molecule an expression vector comprising said polynucleotide an expression system comprising a polynucleotide capable of producing a binding molecule an isolated host cell which comprises an expression system as defined above the use of such binding molecule as a pharmaceutical, especially in the treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system a pharmaceutical composition comprising said binding molecule and a method of treatment of a disease of the peripheral (PNS) and/or central (CNS) nervous system.
