A laundry additive composition is provided that includes at least one zeta potential modifier, a fluoropolymer, a hydrophobic agent with a melting point or glass transition temperature below 100° C., and an antimicrobial active for imparting fabric protection benefits to a fabric, such as improved stain and soil resistance, oil repellency, water repellency, softness, wrinkle and damage resistance, and better hand feel, as well as imparting microbiocidal or microbiostatic properties to the fabric and/or washing machine surfaces. Laundry additive compositions can be used as a pretreatment prior to washing, through soaking a fabric or garment. Alternately, they can be added to a washing treatment liquor that comprises either the wash or rinse cycle of an automatic washing machine, to first provide and then maintain and refresh fabric protection benefits imparted to the fabric. Following use of a first treatment composition, protective benefits are maintained and refreshed by means of a second treatment operatio
