Compounds derived from substituted propionic acid - 3 - heteroaroilamino, cathepsin like protease inhibitors, Preparation Method, Pharmaceutical composition that comprises； and its use for the treatment of heart failure, immunological diseases, Asthma, Pain, among other S.
The present invention relates to compounds of the formula I, wherein A, D, E, L, G, R10, R30, R40, R50 and R60 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease cathepsin A, and are useful for the treatment of diseases such as atherosclerosis, heart failure, renal diseases, liver diseases or inflammatory diseases, for example. The invention furthermore relates to processes for the preparation of the compounds of the formula I, their use and pharmaceutical compositions comprising them.COMPUESTOS DERIVADOS DE ACIDO 3-HETEROAROILAMINO-PROPIONICO CON ACTIVIDAD INHIBIDORA DE PROTEASA CATEPSINA A； COMPOSICION FARMACEUTICA； PROCEDIMIENTO DE PREPARACION； USO EN EL TRATAMIENTO DE INSUFICIENCIA CARDIACA, INFARTO AL MIOCARDIO, ATEROSCLEROSIS, INSUFICIENCIA RENAL, ENFERMEDADES INMUNOLOGICAS, ARTRITIS REUMATOIDE, HIPERTENSION.
