AHMAD, SALEEM,LI, LING,NEGASH, LIDET A.,HYNES, JOHN
申请号：
CA3062602
公开号：
CA3062602A1
申请日:
2018.05.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed are compounds of Formula (I) or a salt or prodrug thereof, wherein: X is CR4 or N； Y is CR5 or N； provided that only one of X and Y is N； (R1) is: or； wherein R1, R1a, R1b, R1c, R2, and R3 are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.
