VACCARO, WAYNE,CHEN, ZHONG,DODD, DHARMPAL S.,HUYNH, TRAM N.,LIN, JAMES,LIU, CHUNJIAN,MUSSARI, CHRISTOPHER P.,TOKARSKI, JOHN S.,TORTOLANI, DAVID R.,WROBLESKI, STEPHEN T.
申请号：
HRP20130155
公开号：
HRP20130155T1
申请日:
2013.02.25
申请国别(地区):
HR
年份:
2013
代理人:
摘要：
Compounds having the formula (1), and enantiomers, and diastereomers, pharmaceutically-acceptable salts, thereof, are usefuil as kinase modulators, including MK2 modulation, wherein one of E and F is a nitrogen atom and the other of E and F is a carbon atom, Z is N or CR<；SUB>；3<；/SUB>；, and R<；SUB>；1<；/SUB>；, R<；SUB>；2<；/SUB>；, R<；SUB>；3<；/SUB>；, X and Y are as defined herein.
