MEZO, Adam R,Rivera, Daniel S,Bitoni, Alan J,Stattel, James M,Low, Susan C,Peters, Robert T.
申请号：
DK10182902
公开号：
DK2357196T3
申请日:
2004.05.06
申请国别(地区):
DK
年份:
2016
代理人:
摘要：
A chimeric protein is synthesized by a) recombinantly expressing a fusion protein comprising at least a portion of an immunoglobulin constant region and a splicing protein capable of forming a C terminus thioester on the portion of an immunoglobulin constant region； b) adding a thiol cofactor to the fusion protein of a)； and c) adding at least one biologically active molecule having an N terminal cysteine.
