N-PHENYLPIPERAZINE DERIVATIVES THAT ARE ANTAGONISTS OF A1A, A1D ADRENOCEPTORS AND 5-HT1A RECEPTORS FOR THE TREATMENT OF BENIGN PROSTATE HYPERPLASIA, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
MARTINS DA SILVA, CLAUDIA LUCIA,CHAGAS DA SILVA, FERNANDA,CHAVES BARBERATO, LUANA,DE CAMARGO NASCENTE, LUCIANA,BARBOSA DO NASCIMENTO VIANA, JESSICA,OLIVEIRA SILVA, RENATA,NUNES LEMES, LAÍS FLÁVIA,GERM
申请号:
EP13733873
公开号:
EP2810938A4
申请日:
2013.01.04
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention provides N-phenylpiperazine derivatives for use as multiple binders and/or antagonists of α1A adrenoceptors, α1D adrenoceptors and 5-HT1A serotonin receptors. These substances are candidates to prototypes for the treatment of benign prostate hyperplasia and lower urinary tract symptoms, and are useful in pharmaceutical compositions.