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DÉRIVÉS DE BIARYLE EN TANT QU'AGONISTES DE GPR120
专利权人:
LG LIFE SCIENCES LTD.
发明人:
KIM, YOUNG KWAN,PARK, SANG YUN,JOO, HYUN WOO,CHOI, EUN SIL
申请号:
EP14818620
公开号:
EP3013796A4
申请日:
2014.06.26
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to biaryl derivatives of Formula 1, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The biaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in the liver or in muscle due to anti-inflammatory action in macrophages, lipocytes, etc., and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, obesity, non-alcoholic fatty liver, steatohepatitis, osteoporosis or inflammation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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