The present invention provides a composition comprising a corticosteroid and an insulin analog. Further provided is a composition comprising a corticosteroid, insulin lispro and at least one organic acid. The present invention also provides methods of stimulating bone and/or cartilage growth by administering the formulation described herein for the treatment of bone fractures and cartilage damage. Further provided are the methods for the treatment of tumors and cysts of the jaw by administering the formulation described herein.
