METHOD FOR PREDICTION OF RISK OF VENTRICULAR TACHYARRHYTHMIAS IN PATIENTS SUFFERING MYOCARDIAL INFARCTION WITH LEFT VENTRICULAR EJECTION FRACTION LESS THAN 35 %
Atabekov Tariel Abdilazimovich (RU),Атабеков Тариель Абдилазимович (RU),Botalov Roman Efimovich (RU),Боталов Роман Ефимович (RU),Sazonova Svetlana Ivanovna (RU),Сазонова Светлана Ивановна (RU),Popov S
申请号：
RU2019125399
公开号：
RU0002722656C1
申请日:
2019.08.09
申请国别(地区):
RU
年份:
2020
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to cardiology. Prognostic factors are determined from the analysis of heart rate variability by formula 1where PCHRV - predictive coefficient from heart rate variability, AHR - average heart rate, ANN - average NN-interval, SDNN - standard deviation of all NN-intervals, SDANN is the standard deviation of the average values of the NN-intervals calculated at 5-minute intervals throughout the recording, ASDNN is the average value of the standard deviations of the NN-intervals calculated at 5-minute intervals throughout the recording, rMSSD is the square root of the average sum of squares of differences between adjacent NN-intervals, pNN50 is the percentage of NN50 from the total number of consecutive pairs of NN-intervals, differing by more than 50 ms, obtained over the entire recording period, VLF is a very low-frequency spectral component, LF is a low-frequency spectral component, HF is a high-frequency spectral component, TF is a total number of spectral components, LF/HF is ratio of low-frequency spectral component to high-frequency spectral component. Prognostic coefficients are determined by analyzing single-photon emission computed tomography of the myocardium with meta-iodine-benzylguanidine, labeled with iodine-123 by formula 2where PCs is a prognostic coefficient according to scintigraphic indices, SSe is an iodine-123-marked meta-iodine-benzyl guanidine accumulation defect on early scintigrams, SSd is an iodine-123-marked meta-iodine-benzyl guanidine accumulation defect on late scintigrams. If the heart rate variability is more than 1.129 and the single photon emission myocardial emission tomography is reduced to 2.777 and less, a high risk of developing ventricular tachyarrhythmias is predicted.EFFECT: method enables higher clinical effectiveness in the patients with a high risk of ventricular tachyarrhythmias and sudden cardiac death, as well as enables optimizing the selection of candidate c
