A locking mechanism assembly to allow locking of a fastener in an orthopedic implant having its axis at a variable angle relative to the axis of a concavely rounded through opening in the implant. The assembly includes a convexly rounded ring shaped locking cam insert which mates with the through opening and further which includes an expansion slot. The cam insert includes two cam raceways on the inside that are engaged by cam members on the head of the fastener. The cam members increase radially and expand the insert in the through opening to hold it in position by friction. The cam insert further includes a stop member that inhibits the cam insert from rotating as the fastener is rotated in the cam insert and locks it into the desired position.