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Oral Administration of an Anti-CD20 Antibody for Treatment of Autoimmune Disease
专利权人:
Staley A. Brod
发明人:
Staley A. Brod
申请号:
US15063822
公开号:
US20170260283A1
申请日:
2016.03.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides a method for treating or delaying the onset of an autoimmune condition in a human subject. An effective oral dose of an anti-CD20 antibody is administered to the subject. Oral administration of such antibodies as rituximab, ocrelizumab, ofatumumab, obinutuzumab, tositumomab, or ibritumomab are useful in a method of decreasing innate inflammatory cytokines, such as and TNF-a, IFN-g, IL-17, and IL-12.
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